Alcoholic liver disease is a common problem in developing countries. There was no correlation between the type of alcoholic beverage and liver disease. The amount and duration of alcohol consumption are important factors in the onset of the disease. Also, factors such as gender, genetic factors, tobacco use, hepatitis B, hepatitis C, non-alcoholic fatty liver disease and being overweight also play a role.
About 35-40 percent of those who consume 10 to 80 milligrams of alcohol per day develop fatty liver, which is considered a moderate amount, Assoc. Dr. Gürol Öksüzoğlu, “Hepatitis and cirrhosis develop in 20-25 percent of those who consume heavy alcohol. It is known that at least 30-40 grams of alcohol should be consumed daily for the development of alcoholic hepatitis. Consumption of more than 80 grams of alcohol per day increases the severity of alcohol-related hepatitis. The higher the dose, the higher the risk of cirrhosis. Drinking more than 60 grams of alcohol per day in men and more than 20 grams in women significantly increases the risk of cirrhosis.
Cirrhosis occurs when the liver loses its function
Refers to how alcohol affects the liver, Assoc. Dr. Gürol Öksüzoglu, “Liver and gastrointestinal systems break down and alcohol is metabolized. Alcohol consumption reduces glucose production and fatty acid breakdown. Toxic molecules and reactive oxygen type cells are formed, liver cells are damaged and swollen, and fibrosis-scar tissue formation begins. As a result of this process, the liver can lose its function and lead to cirrhosis.
The last resort is a liver transplant
Alcohol consumption causes three types of alcoholic liver disease.
Fatty liver: This is usually completely resolved when we stop drinking alcohol. In most cases there are no complaints or there may be mild weakness, loss of appetite, right upper abdominal pain and nausea. Adequate medical treatment and proper diet are sufficient. In case of fatty liver, if alcohol consumption is continued, the chance of developing cirrhosis within 5 years is 8%.
Alcoholic hepatitis: There may be no complaints, or loss of appetite, weakness, weight loss, abdominal pain, bloating, nausea, vomiting, itching, jaundice, itching, and in advanced cases, changes in consciousness, coma, and in some cases, liver failure and death. Can In severe cases, drug therapy is recommended. If alcohol consumption continues in patients, the chances of developing cirrhosis within 5 years are 16%.
Alcoholic cirrhosis: Varicose veins can develop in patients with splenomegaly, fluid retention, liver failure, and liver cancer. Weakness, loss of appetite, weight loss, muscle wasting, edema, shortness of breath, bloody vomit, black stools, fever, itching, kidney and lung failure, change of consciousness, coma, jaundice. Medications, diet, surgical intervention, interventional radiological procedures, and more recently a liver transplant are recommended.
Psychiatrist and dietitian support is required
With the help of psychiatrists and dietitians, the mainstay of treatment is alcohol withdrawal, Assoc. Dr. Öksüzoglu says: “In most cases there is malnutrition, so the help of a dietitian is needed. Although oral nutrition is preferred, in some cases intravenous nutrition may be needed. If malnutrition is not eliminated, the disease progresses significantly and the risk of death In some cases, appropriate drug therapy is on the agenda. As the severity of liver disease increases, hospitalization and intravenous treatment of the patient becomes more important. , Kidney failure that may develop in liver disease may need to be treated with special medications. Sometimes, endoscopic intervention, “surgery, interventional radiological procedures may be required. Even if the patient develops cirrhosis of the liver or very severe cases of alcoholic hepatitis, liver transplantation is used as a last resort. “